MDI Whole Blood Separator  Introduction 
Advancements in blood separation research MDI at has resulted in a unique set of Red Blood Cell (RBC) separation materials which satisfy the long standing demands of the lateral flow diagnostic test manufacturing industry. Blood separaqtors are useful as they offer following advantages to a point of care rapid test manufacturer.
Eliminates the need for storage
centrifugation or clotting of blood samples.
No technical expertise and lag equipment is required.
True one step method. No liquid buffer is required in the kit.
On the spot results in critical situations.
Results are reliable as intermixing of patient's sample is avoided

Commonly Faced Problems with Blood Separator	Solutions offered by mdi Blood Separator WFR1
Leakage of RBC on the memberane is very slow resulting in delayed results.	Higher void volume and extermely high retention efficIency results in full stoppage of RBC
The migration of plasma on the memberane is very slow resulting in delayed results	The unique composite design faciliates faster migration of plasma through the seprator
High volume of blood is required due to poor plasma recovery.	The unique composite structure allows high plasma recovery making it possible to make one step whole blood assays with as little as 25 whole blood
The seaprator may work for fingerprick blood but does not work stored blood (with anticoagulant)	separators work well with fingerprick as well as stored blood
The separator absorbs the analyte resulting in reduced sensitivity	The absorption of the analyte in minimal resulting in higher sensitivity

Modes of whole blood test Kits
Whole blood lateral flow are designed in two distinct modes

Mode 1: A liquid buffer is provioded with the test kit to drive the plasma through the sample pad and the membrane to complete the assay. Minimal quantity of whole blood can be used.

Mode 2 : The test kit does not contain any liquid buffer. Plasma separated from applied whole blood itself migrates up the membrane to comnplete the assay.

Format Design

Mode 1 : Blood separator FR1 acts as the sample pad and will stop the RBC . Typically 5- 50 whole blood is applied in the holwe of the device and 2-3 drops of buffer are added to drive the plasma. A separate conjuate release pad is required.

Mode 2: The Polyester matrix of WFR1 stops some RBC allowing free flow of plasma whereas the white matrix stops the reamining RBC completely allowing only plasma to flow through the NC membrane . Due to the design and construstion of above material the RBC do not leak to the membrane assuring a valid assay, even if excess blood is applied. To conseve plama and enhance the speed of flow . WFR1 also as conjuate release matrix. The format design is shown in fig.2

Typically 2- 3 drops of whole blood is required . However by proper design of a dipstick with reduced dimensions, tests can be made to run with only one drop of whole blood.

Ordering Information
FR1 is available in roll from slit to desired width with 0.35mm and 0.65mm thickness
WFR1 is available only in strip fromupto 30cm long.Width is customer specified as required as required to fit the cassette/dipsticks.